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NCI Surgery Branch Seeks Innovative Partnership for Cancer Treatment Breakthrough

In an development for cancer research, the National Cancer Institute's Surgery Branch is reaching out to potential partners in the pharmaceutical industry. Their goal? To combine cutting-edge vaccine technology with advanced cell therapy techniques in the fight against cancer.

Human Colon Cancer Cells - Credit: NCI Center for Cancer Research

The Collaboration

The NCI Surgery Branch, led by the renowned Dr. Steven Rosenberg, is looking for a partner capable of producing a GMP-grade vaccine targeting cancer neo-antigens. This vaccine would work in tandem with engineered T cells developed using the NCI's proprietary methods.


The ultimate aim is to conduct a Phase I clinical trial for solid cancers, potentially paving the way for more effective treatments for patients with advanced forms of the disease.

What NCI Brings to the Table

  • Expertise in TIL and TCR-transduced PBL development

  • Ability to provide GMP-Grade TILs or PBLs

  • Patient recruitment and trial conduction at NCI facilities

The Ideal Partner

The NCI is seeking an industry collaborator with expertise in vaccine manufacture. This partner would be responsible for providing the GMP-grade vaccine to be used alongside the NCI's engineered T cells.


About Dr. Steven Rosenberg

Dr. Rosenberg, Chief of the Surgery Branch at NCI's Center for Cancer Research, is a pioneer in cancer immunotherapy. His groundbreaking work has led to durable complete remissions in patients with advanced solid cancers. Dr. Rosenberg's current research focuses on understanding and harnessing the host immune response to cancer.


Moving Forward

This collaboration represents a significant opportunity to advance cancer treatment. Interested companies can contact Aida Cremesti, Senior Technology Transfer Manager at the NCI Technology Transfer Center, for more information.


For more details on this partnership opportunity, visit: NCI Technology Transfer Center


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